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PERBETE

Skincare ingredients for sun protection

Our research data links 37 ingredients to sun protection. Strongest evidence comes first, each with the studies behind it.

A research list, not medical advice. If a skin condition worries you, see a dermatologist.

Which ingredients have the most evidence for sun protection?

In our data, the strongest evidence for sun protection is behind Isoamyl p-Methoxycinnamate (Amiloxate), Avobenzone, and Benzylidene Camphor Sulfonic Acid.

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Top 5 at a glance
IngredientEvidenceStudied atRating
Isoamyl p-Methoxycinnamate (Amiloxate)🏛 Regulatory evidenceEU limit 10%Low concern
Avobenzone🏛 Regulatory evidenceEU limit 5%Low concern
Benzylidene Camphor Sulfonic Acid🏛 Regulatory evidenceEU limit 6% (acid equivalent)Low concern
Bemotrizinol🏛 Regulatory evidenceEU limit 10%; US final limit 6%Low concern
Bisdisulizole disodium🏛 Regulatory evidenceEU limit 10% (acid equivalent)Low concern
  1. Isoamyl p-Methoxycinnamate

    Studied at EU limit 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 189 products

  2. AvobenzoneLow concern

    Butyl Methoxydibenzoylmethane

    Studied at EU limit 5%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 720 products

  3. Studied at EU limit 6% (acid equivalent)

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  4. BemotrizinolLow concern

    Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

    Studied at EU limit 10%; US final limit 6%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union
    • Reference: FDA, 2026
    • Reference: FDA, 2026

    Pregnancy: not rated yet · Listed in 1,015 products

  5. Disodium Phenyl Dibenzimidazole Tetrasulfonate

    Studied at EU limit 10% (acid equivalent)

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 1 product

  6. Benzophenone-5

    Studied at EU limit 5% combined with BP4 (acid equivalent)

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 111 products

  7. Studied at EU limit 6%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  8. Studied at EU limit 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 98 products

  9. Studied at EU limit 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union
    • Reference: European Commission, 2026

    Pregnancy: not rated yet · Listed in 1,006 products

  10. Studied at EU limit 15%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 139 products

  11. EcamsuleLow concern

    Terephthalylidene Dicamphor Sulfonic Acid

    Studied at EU limit 10% (acid equivalent)

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 235 products

  12. Studied at EU limit 5%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 630 products

  13. EnsulizoleLow concern

    Phenylbenzimidazole Sulfonic Acid

    Studied at EU limit 8% (acid equivalent)

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 250 products

  14. Bis-(Diethylaminohydroxybenzoyl Benzoyl) Piperazine

    Studied at EU limit 10% nano combined

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  15. Studied at EU limit combined with non-nano 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  16. HomosalateModerate concern

    Studied at EU limit 7.34% face only; propellant spray excluded

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: use with care · Listed in 614 products

  17. BisoctrizoleLow concern

    Methylene Bis-Benzotriazolyl Tetramethylbutylphenol

    Studied at EU limit 10% nano combined

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 216 products

  18. Studied at EU limit combined with non-nano 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  19. Studied at EU limit 3%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 3 products

  20. OctisalateModerate concern

    Ethylhexyl Salicylate

    Studied at EU limit 5%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 1,235 products

  21. OctocryleneLow concern

    Studied at EU limit 10%; propellant spray 9%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 649 products

  22. OctinoxateLow concern

    Ethylhexyl Methoxycinnamate

    Studied at EU limit 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: use with care · Listed in 1,070 products

  23. OxybenzoneModerate concern

    Benzophenone-3

    Studied at EU 6%; face, hands and lips spray excluded; body 2.2%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: use with care · Listed in 52 products

  24. Studied at EU limit 6%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  25. Padimate OLow concern

    Ethylhexyl Dimethyl PABA

    Studied at EU limit 8%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 1 product

  26. Studied at EU limit 5%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  27. PEG-25 PABALow concern

    Studied at EU limit 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Not in our product list yet

  28. Polysilicone-15Low concern

    Studied at EU limit 10%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 345 products

  29. SulisobenzoneLow concern

    Benzophenone-4

    Studied at EU limit 5% (acid equivalent); combined with BP5

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 92 products

  30. Studied at EU limit 10% specification nano

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 2 products

  31. Titanium dioxideLow concern

    Studied at EU limit 25%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not advised against on skin · Listed in 3,361 products

  32. Studied at EU limit combined with non-nano 25%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 4 products

  33. Zinc oxideLow concern

    Studied at EU limit 25%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not advised against on skin · Listed in 1,215 products

  34. Studied at EU limit combined with non-nano 25%

    Not a score for the SPF or skin-cancer prevention effect of an individual filter. Optical testing of the whole composition is needed, including crystal form, particle size, dissolution and film.

    • Reference: European Union

    Pregnancy: not rated yet · Listed in 3 products

  35. CI 77491

    Studied at N/A; finished-product visible-light blocking test needed

    An auxiliary pigment for visible-light protection. Its stand-alone UV-filter score is 1.0; keep the effect of finished products for melasma prevention apart, as in sections 4 and 15 and the formulation table.

    • Reference: Castanedo-Cazares et al., 2014

    Pregnancy: not rated yet · Listed in 1,221 products

  36. CI 77499

    Studied at N/A; finished-product visible-light blocking test needed

    An auxiliary pigment for visible-light protection. Its stand-alone UV-filter score is 1.0; keep the effect of finished products for melasma prevention apart, as in sections 4 and 15 and the formulation table.

    • Reference: Castanedo-Cazares et al., 2014

    Pregnancy: not rated yet · Listed in 551 products

  37. CI 77492

    Studied at N/A; finished-product visible-light blocking test needed

    An auxiliary pigment for visible-light protection. Its stand-alone UV-filter score is 1.0; keep the effect of finished products for melasma prevention apart, as in sections 4 and 15 and the formulation table.

    • Reference: Castanedo-Cazares et al., 2014

    Pregnancy: not rated yet · Listed in 890 products

Which ingredients for sun protection are advised against in pregnancy?

None of the 37 ingredients here carries an 'advised to avoid' verdict for pregnancy in our data.

Use with care (the reason is on each ingredient page): Homosalate, Octinoxate, and Oxybenzone.

Pregnant or breastfeeding? Check new products with your doctor or midwife.

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