Tocopheryl acetate

Tocopheryl acetate

Low hazardMolecular weight 472.7

What does Tocopheryl acetate do for skin?

The phenolic OH is acetylated, so direct radical scavenging is limited; hydrolysis is needed. Cannot be substituted one-to-one for free alpha-tocopherol 1%.

Dose on file: N/A

Is Tocopheryl acetate safe in skincare?

Low hazardHazard 2/10

CIR safe as used

Based on

  • Reference: CIR

    Safe as used · CIR: safe as used at reported concentrations.

  • Reference: Korea MFDS

    Country limits · 1 rule across 1 country

Is Tocopheryl acetate classified as a carcinogen?

Only four bodies count here: IARC, EU CLP, US NTP and California Prop 65.

Not classified by IARC, EU CLP, US NTP, or California Prop 65.

How is Tocopheryl acetate regulated?

Cosmetic ingredient

Not found on any prescription-drug, professional-treatment, or US OTC monograph list, so it is treated as a cosmetic ingredient. This is a passive default ("not on any known restricted list"), not an individually verified positive finding.

Is Tocopheryl acetate safe during pregnancy?

  • Pregnant

    Considered fine

  • Nursing

    Not enough data

  • Planning

    Considered fine

Tocopheryl acetate is the acetate ester of vitamin E, and CIR assessed the tocopherol family as one group. A review of skin care in pregnancy (Putra 2022) adds vitamin E to its list of moisturiser ingredients that can be used in pregnancy (as an emollient). This is the judgement of one expert review; it is not a study of pregnant women. Vitamin E is also a nutrient we need in pregnancy. We found no data on skin use while nursing (LactMed's vitamin E entry covers supplements by mouth).

  • Reference: Putra IB et al., 2022

    Review (2022): vitamin E can be used as an emollient in pregnancy · Listed after the moisturiser ingredients described as safe to use during pregnancy. The authors' own judgement; no study of pregnant women behind it.

  • Reference: Fiume MM et al. (CIR Expert Panel), 2018

    CIR (2018): tocopherols and tocotrienols safe as used in cosmetics · The panel treated 14 tocopherols and tocotrienols (tocopheryl acetate included) as one group. The abstract does not mention pregnancy.

  • Reference: NIH Office of Dietary Supplements, 2021

    NIH fact sheet: vitamin E is a nutrient we need; 15 mg a day recommended in pregnancy · The adult upper limit for vitamin E from supplements is 1,000 mg a day. Context only, not a skin-use verdict.

  • Reference: US NIH / NICHD

    LactMed 'Vitamin E': normal part of milk; skin use not addressed · Relevant published information on effects in breastfed infants was not found.

Tocopheryl acetate benefits for skin, by concern

These raw scores are only shown here, in the ingredient dictionary.

Products that list this ingredient

Sources (6)

  • Reference: CIR
  • Reference: Korea MFDS
  • Reference: Putra IB et al., 2022
  • Reference: Fiume MM et al. (CIR Expert Panel), 2018
  • Reference: NIH Office of Dietary Supplements, 2021
  • Reference: US NIH / NICHD

Red does not mean poison. Preservatives that stop a product going off, UV filters and fragrance can land on yellow or red depending on their score.

Green does not mean right for you. Skin and allergies differ from person to person. Treat the color as a starting point.